METABOLITES OF PATHOGENIC FUNGI: III. THE STRUCTURE OF XANTHOMEGNIN

Abstract

Xanthomegnin, a pigment isolated from Trichophyton megnini, was shown to be (−) 3,3′-bis-[2-methoxy-5-hydroxy-7-(2-hydroxypropyl)-8-carboxy-l,4-naphthoquinone lactone]. Application of the Hudson–Klyne lactone rule (C. S. Hudson, J. Am. Chem. Soc., 32, 338 (1910); W. Klyne, Chem. Ind. (London), 1198 (1954)) gave results which supported the proposed stereochemistry.