Protein kinase C inhibitors potentiate angiotensin II-induced phosphoinositide hydrolysis and intracellular Ca2+ mobilization in renal mesangial cells

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

Tatsuya Tamaoki, Hisayo Nomoto, ISAMI TAKAHASHI et al. · Biochemical and Biophysical Research Communications · 1986 · 2.5K citations

Life Sciences, Biochemistry, Pharmacology +10

Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator.

Roger Y. Tsien, Tullio Pozzan, T J Rink · The Journal of Cell Biology · 1982 · 2.3K citations · Full text

Life Sciences, Biochemistry, Biophysics +13

Rapid accumulation of inositol trisphosphate reveals that agonists hydrolyse polyphosphoinositides instead of phosphatidylinositol

Michael J. Berridge · Biochemical Journal · 1983 · 1.1K citations · Full text

Life Sciences, Biochemistry, Entomology +15

Culture of Normal Human Leukocytes

George E. Moore · JAMA · 1967 · 778 citations

Medicine, Cell Biology, Hematology +10

Protein kinase C

Pharmacology & Therapeutics · 1991 · 406 citations

Medicine, Cell Biology, Oncology +17