Journal of Heterocyclic Chemistry · 1968 · 93 citations · 4 references
Natural SciencesChemistryMedicinal ChemistryOrganic ChemistrySynthetic Medicinal ChemistryHeterocycle ReplacementHeterocycle SynthesisHeterocyclic ChemistryHeterocyclic CompoundsOrganic SynthesisAmino Acid-derived HeterocyclesFuransNitro CompoundsNitro Reduction
Abstract This paper describes the synthesis of the various picrylamino‐ and nitro‐substituted furazans and bifurazanyls. Except for 3,4‐bis(picrylamino)furazan, which was obtained by nitrating 3,4‐dianilinofurazan, the picrylaminofurazans were prepared by condensing the appropriate amino‐furazan with picryl fluoride in the presence of triethylamine. The various aminofurazans were oxidized with peroxytrifluoroacetic acid to the corresponding nitro derivatives.
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