Basic Fibroblast Growth Factor and Insulinlike Growth Factor I Support the Growth of Human Septal Chondrocytes in a Serum-Free Environment

Abstract

The combination of IGF-I and bFGF in a serum-free and a serum-supplemented environment supports the growth and viability of human septal chondrocytes in short-term culture. In an SFM, the results obtained approximate those produced in a medium enhanced with 10% fetal calf serum.