Identification of a Molecular Profile Associated with Immune Status in First-Onset Schizophrenia Patients

Marlis Herberth, Hassan Rahmoune, Emanuel Schwarz, Dagmar Koethe, Laura W. Harris, Laura Kranaster, Stephanie H. Witt, Michael Spain, Anthony Barnes, Manfred Schmolz,

Clinical Schizophrenia & Related Psychoses · 2013 · 34 citations · 13 references

Concepts

Abstract

This study has identified a reproducible peripheral molecular signature associated with altered immune function in first-onset schizophrenia subjects. This suggests that immune status can affect the biomarker profile which could be important for personalized medicine strategies. Furthermore, whole blood culture analysis may be useful in the identification of diagnostic tools or novel treatment strategies due to ease-of-use and clinical accessibility.

References

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