Effects of environmental enrichment and paradoxical sleep deprivation on open-field behavior of amphetamine-treated mice

Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.

G. Di Chiara, Assunta Impérato · Proceedings of the National Academy of Sciences · 1988 · 4.7K citations · Full text

Psychopharmacology, Pharmacotherapy, Synaptic Dopamine Concentrations +18

Long-Term Environmental Enrichment Leads to Regional Increases in Neurotrophin Levels in Rat Brain

Brian Ickes, Therese Pham, Linda Sanders et al. · Experimental Neurology · 2000 · 538 citations

Neurophysiology, Neuroanatomy, Regional Increases +11

Environmental enrichment in mice decreases anxiety, attenuates stress responses and enhances natural killer cell activity

Noa Benaroya-Milshtein, Nurit Hollander, Alan Apter et al. · European Journal of Neuroscience · 2004 · 434 citations

Role of hippocampal oxidative stress in memory deficits induced by sleep deprivation in mice

Regina H. Silva, Akihiro Takatsu, Sonia R. Kameda et al. · Neuropharmacology · 2004 · 305 citations

Memory Deficits, Sleep, Memory System +10

Environmental enrichment decreases intravenous self-administration of amphetamine in female and male rats

Michael T. Bardo, Jennifer E. Klebaur, Joanne M. Valone et al. · Psychopharmacology · 2001 · 293 citations

Substance Use, Psychopharmacology, Environmental Enrichment +16