Cellular Uptake and Saccharide Chain Elongation of “Fluoro-amphiphilic” Glycosides

Abstract

Abstract “Fluoro-amphiphilic” glycosides are practical alternatives for the preparation of oligosaccharides. Fluoro-amphiphilic saccharide primers possessing a hydrophilic sugar moiety and a fluorous tag could be taken up by cells and elongated by cellular enzymes. The elongated products were released by cells to the culture medium and could be easily separated from other components by simple extraction with a fluorous solvent.