Publication | Closed Access
Improved Chromatographic Resolution from Pressure-Induced Changes in Liquid—Solid Distribution Ratios
40
Citations
8
References
1969
Year
High Hydrostatic PressureSupercritical Fluid ChromatographyPreparative ApplicationChemistrySeparation ScienceGas ChromatographyAnalytical ChemistryLiquid ChromatographyClinical ChemistryBiophysicsChromatographyHigh-pressure Liquid ChromatographChromatographic AnalysisDistribution RatioPharmacologyLiquid—solid Distribution RatiosMedicineHigh PressuresDrug Analysis
Abstract A high-pressure liquid chromatograph is described which will deliver eluent under pressures up to 60000 lb/in.2 This instrument is compared to other common liquid chromatographic methods using Methyl and Ethyl Orange on silica. High pressures had a marked effect upon each distribution ratio and improved the separation.
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