Metabolite concentrations in supraventricular white matter from teenage to early old age: A short echo time ¹h magnetic resonance spectroscopy (MRS) study

Abstract

The concentrations of several metabolites in cerebral supraventricular white matter are age dependent on (1)H MRS, even in young and middle-aged people, and age dependency can be nonlinear. Each (1)H MRS study of the brain should therefore take age into account, whereas sex does not appear to be so important. The use of macromolecule and lipid evaluations is compromised by less successful quantification and large variations in healthy people.