Topical use of tranexamic acid in coronary artery bypass operations: A double-blind, prospective, randomized, placebo-controlled study

Mechanism of abnormal bleeding in patients undergoing cardiopulmonary bypass: acquired transient platelet dysfunction associated with selective alpha-granule release.

Laurence A. Harker, Thomas W. Malpass, Herman Branson et al. · PubMed · 1980 · 663 citations

Medicine, Hematology, Surgery +17

Aprotinin therapy for reoperative myocardial revascularization: A placebo-controlled study

Delos M. Cosgrove, Blaine Heric, Bruce W. Lytle et al. · The Annals of Thoracic Surgery · 1992 · 388 citations

Medicine, Cardiology, Surgery +15

Hemostatic Effect of Tranexamic Acid Mouthwash in Anticoagulant-Treated Patients Undergoing Oral Surgery

Steen Sindet‐Pedersen, G. Ramström, S.S. Bernvil et al. · New England Journal of Medicine · 1989 · 282 citations

Medicine, Pharmacotherapy, Anesthesia +16

Analyses of coronary graft patency after aprotinin use: Results from the international multicenter aprotinin graft patency experience (IMAGE) trial

Edwin L. Alderman, Jerrold H. Levy, Jeffrey Rich et al. · Journal of Thoracic and Cardiovascular Surgery · 1998 · 251 citations · Full text

Medicine, Cardiology, Surgery +11

Prospective evaluation and clinical utility of on-site monitoring of coagulation in patients undergoing cardiac operation

George J. Despotis, Samuel A. Santoro, Edward L. Spitznagel et al. · Journal of Thoracic and Cardiovascular Surgery · 1994 · 228 citations · Full text

Medicine, Cardiology, Perioperative Medicine +15