The −159<i>C/T</i> Polymorphism in the Promoter Region of the <i>CD14</i> Gene Is Associated With Advanced Liver Disease and Higher Serum Levels of Acute‐Phase Proteins in Heavy Drinkers

Abstract

Our results support the notion that CD14/-159TT homozygous heavy drinkers have higher levels of the LPS-binding acute-phase proteins (LBP and sCD14) than do carriers of the CD14/-159C allele. Also, the CD14/-159TT genotype may be a risk factor for advanced ALD.