CSF IgG heavy-chain bias in patients at the time of a clinically isolated syndrome

Recommended diagnostic criteria for multiple sclerosis: Guidelines from the international panel on the diagnosis of multiple sclerosis

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Medicine, Internal Medicine, Neurology +10

Treatment with interferon beta-1b delays conversion to clinically definite and McDonald MS in patients with clinically isolated syndromes

Ludwig Kappos, C. H. Polman, Mark S. Freedman et al. · Neurology · 2006 · 677 citations

Life Sciences, Neurology, Pharmacotherapy +12

Treatment with interferon beta-1b delays conversion to clinically definite and McDonald MS in patients with clinically isolated syndromes

Ludwig Kappos, Chris H. Polman, Mark S. Freedman et al. · American Journal of Ophthalmology · 2006 · 551 citations

Life Sciences, Neurology, Pharmacotherapy +12

Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction

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Life Sciences, Immunology, Molecular Biology +17

Clonal expansion and somatic hypermutation of V(H) genes of B cells from cerebrospinal fluid in multiple sclerosis.

Y Qin, Pierre Duquette, Y Zhang et al. · Journal of Clinical Investigation · 1998 · 324 citations · Full text

Life Sciences, Immunology, Neurology +17