European Journal of Organic Chemistry · 2004 · 167 citations · 27 references
Natural SciencesChemical EngineeringChemistryCatalysisOrganic ChemistryReaction EngineeringCatalyst DesignCatalyst PreparationCatalyst SynthesisCatalytic MaterialsCatalytic Reaction EngineeringIndustrial Catalytic ProcessesAldehydesCatalyst Structure - Activity RelationshipsCatalyst Structure-activity RelationshipsCatalytic SynthesisIonic Liquid CatalysisIonic Liquid SynthesisIonic LiquidsMolecular Catalysts
Abstract An efficient synthesis of bis(indolyl)methanes through Fe III ‐catalyzed electrophilic substitution reactions of indoles with various aldehydes in ionic liquid is described. It was found that the ionic liquids involving FeCl 3 ·6H 2 O were the most efficient catalytic systems, and could be simply recycled without significant loss of activity. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
27