In vivo Interaction of 4-Nitroquinoline-l-oxide and its Derivatives with DNA

An Improved Preparation of Sodium Desoxyribonucleate

Ernest Kay, Norman S. Simmons, Alexander L. Dounce · Journal of the American Chemical Society · 1952 · 932 citations

Bioorganic Chemistry, Engineering, Altmetric Attention Score +17

Carcinogenic action of 4-nitroquinoline-N-oxide.

Waro Nakahara, Fumiko Fukuoka, Takashi Sügimura · PubMed · 1957 · 174 citations

Reactive Nitrogen Specie, Medicine, Toxicology +4

Interaction of polynuclear aromatic hydrocarbons, 4‐nitroquinoline 1‐oxides, and various dyes with DNA

Chikayoshi Nagata, Masahiko Kodama, Yusaku Tagashira et al. · Biopolymers · 1966 · 131 citations

Bioorganic Chemistry, Dna, Engineering +19

The metabolism of 4-nitroquinoline-1-oxide, a carcinogen. 3. An enzyme catalyzing the conversion of 4-nitroquinoline-1-oxide to 4-hydroxyaminoquinoline-1-oxide in rat liver and hepatomas.

Takashi Sügimura, Kazuko Okabe, Minako Nagao · PubMed · 1966 · 130 citations

Aldo-keto Reductase, Redox Biology, Oxidative Stress +18

Interaction of the Water-Soluble Carcinogen 4-Nitroquinoline <i>N</i> -Oxide with DNA

Martin F. Malkin, Arthur C. Zahalsky · Science · 1966 · 47 citations

Chromatin, Nucleic Acid Chemistry, Biochemistry +11