Noninvasive Quantification of Regional Myocardial Metabolic Rate of Oxygen by ¹⁵ O ₂ Inhalation and Positron Emission Tomography

Abstract

Accurate quantification of OEF and MMRO2 is feasible with 15O2 inhalation and PET imaging using both the steady-state and autoradiographic analytical approaches. These studies suggest the applicability of this method for quantitative assessments of regional cardiac oxidative metabolism in clinical studies.