Titration to Target Dose of Bisoprolol vs. Carvedilol in Elderly Patients with Heart Failure: The CIBIS-ELD Trial

Abstract

Overall tolerability to target doses was comparable. The pattern of intolerance, however, was different: bradycardia occurred more often in the bisoprolol group, whereas pulmonary adverse events occurred more often in the carvedilol group. This study is registered with controlled-trials.com, number ISRCTN34827306.