Characterisation and expression analysis of interleukin 2 (IL-2) and IL-21 homologues in the Japanese pufferfish, Fugu rubripes, following their discovery by synteny

Basic local alignment search tool

Stephen F. Altschul, Warren Gish, Webb Miller et al. · Journal of Molecular Biology · 1990 · 94.5K citations

Life Sciences, Bioinformatics, Sequence Analysis +3

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Julie Thompson, Desmond G. Higgins, Toby J. Gibson · Nucleic Acids Research · 1994 · 64.9K citations · Full text

Life Sciences, Bioinformatics, Sequence Analysis +14

The neighbor-joining method: a new method for reconstructing phylogenetic trees.

Naruya Saitou, M Nei · Molecular Biology and Evolution · 1987 · 60.5K citations · Full text

Life Sciences, Bioinformatics, Evolutionary Biology +17

A general method applicable to the search for similarities in the amino acid sequence of two proteins

Saul B. Needleman, Christian D. Wunsch · Journal of Molecular Biology · 1970 · 11.5K citations

Life Sciences, Biochemistry, Bioinformatics +13

Improved tools for biological sequence comparison.

William R. Pearson, David J. Lipman · Proceedings of the National Academy of Sciences · 1988 · 11.3K citations · Full text

Life Sciences, Bioinformatics, Biology +15