A high risk phenotype of hypertrophic cardiomyopathy associated with a compound genotype of two mutated β-myosin heavy chain genes

Prevalence of Hypertrophic Cardiomyopathy in a General Population of Young Adults

Barry J. Maron, Julius M. Gardin, John M. Flack et al. · Circulation · 1995 · 2.3K citations · Full text

Medicine, Cardiology, Internal Medicine +7

A molecular basis for familial hypertrophic cardiomyopathy: A β cardiac myosin heavy chain gene missense mutation

Anja A. T. Geisterfer-Lowrance, Susan Kass, G Tanigawa et al. · Cell · 1990 · 1.4K citations

Medicine, Genetics, Molecular Genetics +10

α-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: A disease of the sarcomere

Ludwig Thierfelder, Hugh Watkins, Calum A. MacRae et al. · Cell · 1994 · 1K citations

Medicine, Genetics, Molecular Genetics +10

Mutations in the cardiac myosin binding protein–C gene on chromosome 11 cause familial hypertrophic cardiomyopathy

Hugh Watkins, David A. Conner, Ludwig Thierfelder et al. · Nature Genetics · 1995 · 589 citations

Medicine, Genetics, Molecular Genetics +10

Mutations in either the essential or regulatory light chains of myosin are associated with a rare myopathy in human heart and skeletal muscle

Karl Poetter, He Jiang, Shahin Hassanzadeh et al. · Nature Genetics · 1996 · 585 citations

Medicine, Genetics, Molecular Genetics +16