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The human gene encoding the heavy chain of the major histocompatibility complex class I-like Fc receptor (FCGRT) maps to 19q13.3
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1996
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Knockout MouseImmunogeneticsSignal TransductionFc ReceptorSignaling PathwayGeneticsHuman Fcgrt GeneImmunologyImmune-related Gene PolymorphismHeavy ChainGene CharacterizationMolecular GeneticsDisease Gene IdentificationGene ExpressionMedicineCell BiologyHuman Gene
FcRn is an Fc receptor that structurally resembles the major histocompatibility complex class I molecule. In this study, we isolated the human gene encoding the heavy chain of FcRn (FCGRT) and mapped it by fluorescence in situ hybridization to chromosome band 19q13.3. Thus, like its mouse counterpart, the human FCGRT gene is located outside the major histocompatibility complex.