Increased blood-brain barrier permeability in type II diabetes demonstrated by gadolinium magnetic resonance imaging

Abstract

Increased BBB permeability with MR imaging was detected in patients with type II diabetes or white matter hyperintensities. Increased permeability of the BBB might account for some of the cerebral effects of type II diabetes, and so possibly also for the effect of other conditions that affect the microvasculature (like hypertension), on the brain.