Quantification of a CH–π Interaction Responsible for Chiral Discrimination and Evaluation of Its Contribution to Enantioselectivity

Abstract

Good things come in small interactions: The high chiral discrimination displayed by a new receptor with ammonium salts of aromatic α-amino acid methyl esters is mainly the result of one of the weakest noncovalent interactions, the CH–π interaction (see picture). The interaction has been identified and quantified, and its contribution to the chiral recognition process has been evaluated. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.