Comparison of Steroid Avoidance in Tacrolimus/Mycophenolate Mofetil and Tacrolimus/Sirolimus Combination in Kidney Transplantation Monitored by Surveillance Biopsy

Abstract

Steroid avoidance in tacrolimus-based immunosuppression with MMF or SRL provides equivalent 2-year patient and graft survival with a low incidence of acute rejection and NODM. SCAR and CAN are lower in TAC/SRL compared to TAC/MMF group. The impact of decreased SCAR and CAN in TAC/SRL group on longer-term graft survival and function is to be evaluated.