Antimicrobial Agents and Chemotherapy · 2004 · 35 citations · 16 references
Life SciencesMolecular BiologyMolecular GeneticsGene ExpressionGenomicsMicrobial GeneticsAntibiotic Resistance GeneticsDrug Transporter GeneticsEfflux-mediated ResistanceMultidrug ResistanceResistance Gene DiscoveryResistance GenesAdenosine Triphosphate-binding Cassette TransportersAtp-binding Cassette TransportersMultidrug Efflux TransportersMultidrug Resistance MechanismsMultidrug Resistance TransportReverse Transcription Polymerase Chain Reaction (Rt-pcr)Transporter-mediated Drug ResistanceTransporter-mediated Multidrug Resistance
Two genes, md1 and md2, coding for multidrug resistance ATP-binding cassette transporters were identified in Mycoplasma hominis PG21. Expression of these two genes, quantified by quantitative competitive reverse transcription-PCR, was significantly increased in ethidium bromide-resistant strains of M. hominis compared to that in M. hominis PG21.
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