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Evaluation of volatile ion-pair reagents for the liquid chromatography–mass spectrometry analysis of polar compounds and its application to the determination of methadone in human plasma

Gas ChromatographyMedicineBioanalysisMass SpectrometryVolatile Ion-pair ReagentsHuman PlasmaAnalytical ChemistryPolar CompoundsLiquid ChromatographyChemistryChromatographic AnalysisPharmacologyChromatographyDrug Analysis