Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

Rosalind C. Lee, Rhonda Feinbaum, Victor Ambros · Cell · 1993 · 12.8K citations · Full text

Life Sciences, Genetics, Molecular Genetics +7

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

Brenda J. Reinhart, Frank J. Slack, Michael Basson et al. · Nature · 2000 · 5K citations

Life Sciences, Molecular Biology, Molecular Genetics +13

Identification of Novel Genes Coding for Small Expressed RNAs

Mariana Lagos‐Quintana, Reinhard Rauhut, Winfried Lendeckel et al. · Science · 2001 · 4.9K citations · Full text

Life Sciences, Developmental Biology, Molecular Biology +16

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

Bruce Wightman, Ilho Ha, Gary Ruvkun · Cell · 1993 · 4.2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +11

An Abundant Class of Tiny RNAs with Probable Regulatory Roles in <i>Caenorhabditis elegans</i>

Nelson C. Lau, Lee P. Lim, Earl G. Weinstein et al. · Science · 2001 · 3.3K citations

Life Sciences, Developmental Biology, Genetics +16