A Physicochemical Approach to Acid-Base Balance in Critically Ill Trauma Patients Minimizes Errors and Reduces Inappropriate Plasma Volume Expansion

Abstract

A PC approach improves acid-base diagnosis accuracy. CONV often miss acidosis (particularly those because of hyperchloremia), alkalosis, and tertiary disorders. Inappropriate volume loading follows in the wake of misinterpretation of increased base deficit using CONV and is avoided using PC. PC-directed therapy normalizes acid-base balance more rapidly than CONV.