Invasion of Cytotrophoblastic (JEG‐3) Cells Is Up‐Regulated by Interleukin‐15 <i>In Vitro</i>

Abstract

Trophoblast invasion and migration, but not proliferation, are enhanced by IL-15. Our results suggest a role for IL-15 in the modulation of MMP-1 secretion by JEG-3 cells. Furthermore, we speculate, that IL-15 might be related to the changes of cell adhesion molecule phenotype during the process of invasion.