JAMA · 1964 · 21 citations · 5 references
MedicineAnesthesiologySurgeryAnesthesiaGeneral AnesthesiaNeuroanesthesiologyAdrenal SurgeryBlood Pressure ManagementCardiovascular Effects Of AnesthesiaEndocrine Tumor SurgeryHemodynamic Response To AnesthesiaPheochromocytoma SurgeryAbdominal Surgical ApproachAutonomic Cardiovascular ControlCardiovascular Autonomic ControlHypotension During AnesthesiaIntraoperative Anesthetic ManagementIntraoperative Blood Pressure ControlIntraoperative HypotensionPerioperative Anesthetic Management
Eleven consecutive cases of pheochromocytoma were successfully diagnosed and surgically cured. The rational anesthetic management of a patient with pheochromocytoma should be based on a firm foundation of applied pharmacology. Cardiovascular control is best maintained symptomatically using phentolamine (Regitine) hydrochloride to control excessive hypertension, and with appropriate vasopressors, whole blood or plasma and possible cortisone acetate, to combat hypotension after the tumor is removed. The advantages associated with the transabdominal surgical approach are stressed. The patient with pheochromocytoma can tolerate anesthesia and the associated surgical procedure well through the combined efforts of the anesthesiologist and surgeon in executing their specific responsibilities.
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Shannon Brunjes, Varner J. Johns, Milton G. Crane · New England Journal of Medicine · 1960 · 143 citations
Medicine, Endocrinology, Surgery +16
Role for Ganglionic Norepinephrine in Sympathetic Synaptic Transmission
E. Costa, Alvin M. Revzin, R. Kuntzman et al. · Science · 1961 · 65 citations
Cationic Shifts and Blood Pressure Regulation
Sydney M. Friedman, Constance L. Friedman, Miyoshi Nakashima · Circulation Research · 1957 · 28 citations · Full text
Medicine, Physiology, Excretion +13