ESTROGEN-PRODUCING SERTOLI CELL TUMORS (ANDROBLASTOMA TUBULARE LIPOIDES) OF THE HUMAN TESTIS AND OVARY. HOMOLOGOUS OVARIAN AND TESTICULAR TUMORS. III.*†

Abstract

IN PREVIOUS publications (1, 2, 3) two series of tumors (homologous) of the testis and the ovary have been established, showing complete morphological congruence in all forms of differentiation: (I) The dysgerminoma series (gonocytoma), and (II) the androblastoma series, forming the basis of an exact histogenetic classification of several special forms of tumor of the ovary, the nature and histogenesis of which have hitherto been doubtful and based on a more or less subjective judgment. This applies, for example, to the so-called mesonephroma ovarii (Schiller 1939 (4)) which displays morphological congruence with embryonal testicular tumors originating from germ cells (2) belonging to the dysgerminoma series (gonocytoma). The virilizing so-called “adrenal tumors” and “luteoma” must also be referred to the androblastoma series, particularly on the basis of transition forms demonstrated between these and the Leydig cells in arrhenoblastomas and on the basis of morphological congruence with morphologically different types of androgen-producing interstitial cell tumors in the testis (3).