Association of TNFd and IL-10 Polymorphisms with Mortality in Unrelated Hematopoietic Stem Cell Transplantation

Abstract

The data demonstrate a significant correlation of the TNFd and IL-10-1064 microsatellite polymorphisms with mortality after unrelated HSCT. They support the hypothesis that simple genomic tests, in addition to precise HLA matching, may contribute to determine prognosis in patients undergoing unrelated HSCT.