Multiple opiate receptors: Support for unique mu, delta and kappa sites

The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.

W R Martin, C. G. Eades, JP Thompson et al. · Journal of Pharmacology and Experimental Therapeutics · 1976 · 3K citations

Medicine, Pharmacology, Veterinary Pharmacology +16

Endogenous opioid peptides: multiple agonists and receptors

John A.H. Lord, Angela A. Waterfield, John Hughes et al. · Nature · 1977 · 2.5K citations

Medicine, Pharmacology, Neuroendocrinology +9

Stereospecific Binding of the Potent Narcotic Analgesic [ ³ H]Etorphine to Rat-Brain Homogenate

Eric J. Simon, Jacob M. Hiller, Irit Edelman · Proceedings of the National Academy of Sciences · 1973 · 1.1K citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Isolation of an endogenous compound from the brain with pharmacological properties similar to morphine

John Hughes · Brain Research · 1975 · 981 citations

Medicine, Neuroscience, Pharmacology +14

Dynorphin-(1-13), an extraordinarily potent opioid peptide.

Alan Goldstein, Shizuko Tachibana, Louise I. Lowney et al. · Proceedings of the National Academy of Sciences · 1979 · 870 citations · Full text

Medicine, Neurobiology, Pharmacology +15