Journal of the American Geriatrics Society · 1991 · 20 citations · 39 references
Public HealthGeriatric MedicineEpidemiologyGeriatricsSurvival AnalysisAnalytic EpidemiologyCardiovascular DiseaseComorbidityMortality AnalysisMortality MeasurementMortality Risk AssessmentBlood PressureGender Differences In LongevityGender Differences In MortalityHematocrit EffectsMortality AssociationsMortality PredictorsPatient Demographic VariablesSystolic Blood Pressure
The length of survival and various risk factors were studied utilizing 408 residents (141 men, 267 women) of a large residential home. The subjects, aged 68 years or more at entry, admitted between 1978 and 1983, were physically independent, continent, and non-diabetic. They were followed until December 31, 1988, by which time 78% had died. The multivariate proportional hazard analysis showed the following entry variables to have the indicated effects on relative mortality rate ratios: 5-years' higher age (+10%, NS), persistent bacteriuria (+13%, NS), abnormal ECG (+26%, NS), current smoking (+63%, P less than 0.01), mildly impaired mobility (+96%, P less than 0.001), higher levels of in-study systolic pressure in 10-mm Hg steps (-4%, NS), higher entry serum cholesterol in 1-mmol/L steps (-7%, NS), and higher hematocrit in 5% steps (-14%, P less than 0.02). Female sex was associated with a +25% (NS) rate ratio; socioeconomic status and body weight were without effect. These data highlight the relative importance of specific factors associated with survival of persons within retirement homes and indicate that: (1) the presence of mild impairment of mobility at entry is by far the strongest predictor of early death; (2) smoking and lower hematocrit also exert important adverse effects; and (3) certain "risk factors", ie elevated systolic blood pressure and serum cholesterol, have a minimal protective effect, if any, in this age group.
39
Sidney Katz, Laurence G. Branch, Michael Branson et al. · New England Journal of Medicine · 1983 · 816 citations