Pediatric and Developmental Pathology · 2005 · 55 citations · 15 references
MedicineOncologyPathologyHistologyHistopathologyTumor PathologyBrain TumorsCentral Nervous System TumorsPediatric Brain TumorsPediatric TumorsCerebellopontine Angle LesionsClear Cell NeoplasmsEpendymoma PathologyGross Differential DiagnosisMalignant Cytologic FeaturesMeningioma PathologyMeningioma RecurrencePediatric Meningioma
Clear cell meningioma (CCM) is a rare variant of meningioma. Only 17 cases have been previously reported in children. Although it has bland cytologic features, it has a higher rate of recurrence than does conventional meningioma. This variant has been reported in sites such as spinal/intradural (lumbar and thoracic), cerebellopontine angle, and supratentorial. The differential diagnosis of CCM includes microcystic meningioma, hemangioblastoma, and clear cell ependymoma. The characteristic histology and immunohistochemistry leads to the diagnosis. We present a case of a 7-year-old boy with a CCM of the cauda equina and a review of pediatric CCM.
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