Concepedia

Publication | Closed Access

Effects of Preoperative Statin Therapy on Cytokines after Cardiac Surgery

DOI

69

Citations

0

References

2006

Year

Oliver J. Liakopoulos, Hilmar Dörge, Jan D. Schmitto, Ulf Nagorsnik, J. Grabedünkel, Friedrich A. Schoendube
The Thoracic and Cardiovascular Surgeon

Abstract

Preoperative statin therapy attenuates the release of pro-inflammatory IL-6 and up-regulates anti-inflammatory IL-10 after cardiac surgery with cardioplegia, but fails to inhibit phosphorylation of myocardial IkappaB-alpha.