Concepedia

TMPRSS2, a Serine Protease Expressed in the Prostate on the Apical Surface of Luminal Epithelial Cells and Released into Semen in Prostasomes, Is Misregulated in Prostate Cancer Cells

Ya‐Wen Chen, Ming‐Shyue Lee, Amanda Lucht, Feng‐Pai Chou, Wei Huang, Thomas C. Havighurst, KyungMann Kim, Jehng-Kang Wang, Toni Antalis, Michael D. Johnson,

American Journal Of Pathology · 2010 · 182 citations · 36 references

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36

Recurrent Fusion of <i>TMPRSS2</i> and ETS Transcription Factor Genes in Prostate Cancer

Scott A. Tomlins, Daniel R. Rhodes, Sven Perner et al. · Science · 2005 · 3.9K citations

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Role of the TMPRSS2-ERG Gene Fusion in Prostate Cancer

Scott A. Tomlins, Bharathi Laxman, Sooryanarayana Varambally et al. · Neoplasia · 2008 · 700 citations · Full text

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Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2.

Biaoyang Lin, Camari Ferguson, James T. White et al. · PubMed · 1999 · 545 citations

, , +17

Catalytic cleavage of the androgen-regulated TMPRSS2 protease results in its secretion by prostate and prostate cancer epithelia.

Daniel Afar, Igor Vivanco, René Hubert et al. · PubMed · 2001 · 285 citations

, , +15

Cloning of the TMPRSS2 Gene, Which Encodes a Novel Serine Protease with Transmembrane, LDLRA, and SRCR Domains and Maps to 21q22.3

Ariane Paoloni‐Giacobino, Haiming Chen, Manuel C. Peitsch et al. · Genomics · 1997 · 276 citations

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