Critical Care · 2014 · 23 citations · 0 references
Veterinary MedicineImmunologyMicrobiologyDiagnostic MicrobiologyMedical MicrobiologySepsisBiomarkers In SepsisClinical Recognition Of SepsisSepsis DiagnosisSepsis PathophysiologySeptic ShockDiagnostic Test ProceduresEndotoxin AssaysEndotoxin DetectionEndotoxin QuantificationEndotoxin TestingEndotoxin-mediated InflammationMicrobiological Diagnostics
The Endotoxin Activity Assay (EAA™; Spectral Diagnostics Inc., Toronto, Canada) is a useful diagnostic test for sepsis due to Gram-negative infection and is based on the reaction of neutrophils to endotoxin complexed with an anti-endotoxin antibody. However, the relations between values of EAA and microbiological data have not been elucidated. Our hypothesis is that EAA values correlate to the results of microbiological cultures and also severity.