Pulmonary Surface Activity in Induced Pulmonary Edema*

Abstract

Induction of acute pulmonary edema in anes- thetized dogs causes a large fall in compliance. out of proportion to lung volume (1), and a sharp increase in venous admixture that can be reversed by forcible inflation of the lungs (2). This pat- tern of abnormal function suggested alveolar clo- sure (1, 2).