Fibroblast growth factor receptor signalling is dictated by specific heparan sulphate saccharides

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

Avner Yayon, Michael Klagsbrun, Jeffrey D. Esko et al. · Cell · 1991 · 2.4K citations

Life Sciences, Biochemistry, Cell Biology +15

Receptor Specificity of the Fibroblast Growth Factor Family

David M. Ornitz, Jennifer S. Colvin, Donald G. McEwen et al. · Journal of Biological Chemistry · 1996 · 1.9K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Requirement of Heparan Sulfate for bFGF-Mediated Fibroblast Growth and Myoblast Differentiation

Alan C. Rapraeger, Alison Krufka, Bradley B. Olwin · Science · 1991 · 1.5K citations

Life Sciences, Cell Biology, Developmental Biology +17

Heparin Structure and Interactions with Basic Fibroblast Growth Factor

Salem Faham, Ronald E. Hileman, Jonathan R. Fromm et al. · Science · 1996 · 804 citations

Life Sciences, Biochemistry, Molecular Biology +16

Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation

Taly R. Spivak-Kroizman, Mark A. Lemmon, John E. Ladbury et al. · Cell · 1994 · 662 citations

Life Sciences, Biochemistry, Molecular Biology +14