[The impact of antepartum injection of hepatitis B immunoglobulin on maternal serum HBV DNA and anti-HBs in the newborns].

Abstract

The administration of three doses of HBIG during the last trimester pregnancy can not reduce the maternal serum HBV DNA levels and the injected HBIG can not be transferred to their newborns. Therefore, there is no sound evidence to support the use of this approach to block mother-to-infant HBV transmission.