Insulin-like growth factor 1 receptor antibody induces rhabdomyosarcoma cell death via a process involving AKT and Bcl-xL

Clonogenic assay of cells in vitro

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Serine Phosphorylation of Death Agonist BAD in Response to Survival Factor Results in Binding to 14-3-3 Not BCL-XL

Jiping Zha, Hisashi Harada, Elizabeth Yang et al. · Cell · 1996 · 2.6K citations · Full text

Life Sciences, Cell Biology, Apoptosis +15

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

Shigeomi Shimizu, Masashi Narita, Yoshihide Tsujimoto et al. · Nature · 1999 · 2.2K citations

Life Sciences, Biochemistry, Molecular Biology +10

Bad, a heterodimeric partner for Bcl-xL and Bcl-2, displaces bax and promotes cell death

Elizabeth Yang, Jiping Zha, Jennifer Jockel et al. · Cell · 1995 · 2.1K citations · Full text

Life Sciences, Cancer Biology, Cell Biology +7

The Structural Basis for 14-3-3:Phosphopeptide Binding Specificity

Michael B. Yaffe, Katrin Rittinger, Stefano Volinia et al. · Cell · 1997 · 1.6K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14