Exploration of structure–activity relationships at the two C-terminal residues of potent 11mer Glucagon-Like Peptide-1 receptor agonist peptides via parallel synthesis

A new stereospecific cross-coupling by the palladium-catalyzed reaction of 1-alkenylboranes with 1-alkenyl or 1-alkynyl halides

Norio Miyaura, Kinji Yamada, Akira Suzuki · Tetrahedron Letters · 1979 · 2.2K citations · Full text

Natural Sciences, Chemistry, Catalysis +12

Hamster preproglucagon contains the sequence of glucagon and two related peptides

Graeme I. Bell, Robert F. Santerre, Guy T. Mullenbach · Nature · 1983 · 640 citations

Life Sciences, Biochemistry, Endocrinology +6

Exon duplication and divergence in the human preproglucagon gene

Graeme I. Bell, Ray Sánchez-Pescador, Paul J. Laybourn et al. · Nature · 1983 · 588 citations

Life Sciences, Genetics, Molecular Genetics +12

The pharmacokinetics, pharmacodynamics, safety and tolerability of NN2211, a new long-acting GLP-1 derivative, in healthy men

Henrik Agersø, Lene Jensen, B. Elbrønd et al. · Diabetologia · 2002 · 506 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +9

Eleven Amino Acid Glucagon-like Peptide-1 Receptor Agonists with Antidiabetic Activity

Claudio Mapelli, Sesha Natarajan, Jean‐Philippe Meyer et al. · Journal of Medicinal Chemistry · 2009 · 73 citations · Full text

Medicine, Endocrinology, Pharmacology +17