Concepedia

Ciproxifan, an H3 receptor antagonist, alleviates hyperactivity and cognitive deficits in the APPTg2576 mouse model of Alzheimer’s disease

Mark E. Bardgett, Natasha N. Davis, Patrick J. Schultheis, Molly S. Griffith

Neurobiology of Learning and Memory · 2010 · 67 citations · 45 references

DOI

Concepts

References

45

Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

Karen Hsiao, Paul F. Chapman, Steven P. Nilsen et al. · Science · 1996 · 4.2K citations

, , +17

The Relationship between Aβ and Memory in the Tg2576 Mouse Model of Alzheimer's Disease

Marcus A. Westerman, Deirdre Cooper-Blacketer, Ami Mariash et al. · Journal of Neuroscience · 2002 · 716 citations · Full text

, , +17

A detailed mapping of the histamine H3 receptor and its gene transcripts in rat brain

Catherine Pillot, Anne Héron, Véronique Cochois et al. · Neuroscience · 2002 · 341 citations

, , +9

Modulation of hippocampal cell proliferation, memory, and amyloid plaque deposition in APPsw (Tg2576) mutant mice by isolation stress

Hongxin Dong, Brian Goico, Maureen V. Martin et al. · Neuroscience · 2004 · 340 citations

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GSK189254, a Novel H3 Receptor Antagonist That Binds to Histamine H3 Receptors in Alzheimer’s Disease Brain and Improves Cognitive Performance in Preclinical Models

Andrew D. Medhurst, A.R. Atkins, I.J.M. Beresford et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 301 citations

, , +13