British Journal of Dermatology · 1972 · 32 citations · 0 references
Veterinary MedicineDermatologyInfectious DiseasesDermatopathologyParasitic Skin DiseaseParasitologyInfectious DermatosesMedical ParasitologyParasitic Disease PathogenesisParasitic InfectionsParasitic PathologyTrematode InfectionsComplement Fixation TestsImmunopathology Of ToxoplasmosisPityriasis LichenoidesToxoplasma Gondii DetectionToxoplasmosis PathogenesisToxoplasmosis PathologyToxoplasmosis Treatment
Summary.— Eleven patients with pitryrisis lichenoides have been tested for toxoplasmosis. In 6 of them the complement fixation test, the intradermal test with toxoplasmin and the Sabin‐Feldman test were repeatedly strongly positive. The same patients reported continuous occupational animal contact. Both the toxoplasma‐positive patients and 3 negative patients were submitted to treatment with pyrimethamine. All 6 toxoplasma‐positive patients responded very favourably: 3 were completely cured. 75 clearance of lesions was obtained in 2 and 50 in one. The 3 toxoplasma‐negative patients failed to improve. The authors believe that Toxoplasma gondii infection may play an aetiological role in pityriasis lichenoides. More observations are needed in order to corroborate or to reject this supposition.