Clathrate-Type Complexation of Cephalosporins withβ-Naphthol

G.J. Kemperman, R. De Gelder, F.J. Dommerholt, P.C. Raemakers-Franken, A.J.H. Klunder, B. Zwanenburg

Chemistry - A European Journal · 1999 · 29 citations · 0 references

Concepts

Abstract

The cephalosporin antibiotics cephalexin, cephradine, cefaclor, and cefadroxil form clathrate-type complexes with β-naphthol in the solid state (depicted here). The crystal structures and packing forces are unraveled.