<i>BRAF^V600E</i> mutation and p27^kip1 expression in papillary carcinomas of the thyroid ≤1 cm and their paired lymph node metastases

Abstract

The authors' data suggested that BRAF(V600E) mutation and p27(Kip1) down-regulation in cancer cells of PTC <or=1 cm may be factors that facilitate tumor-cell growth and progression once these are seeded in the LNs.