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Development of pyrimidine-based inhibitors of Janus tyrosine kinase 3

Jack J. Chen, Kumar Thakur, Michael P. Clark, Steven K. Laughlin, Kelly M. George, Roger G. Bookland, Jan R. Davis, Edward J. Cabrera, Vijay Easwaran, Biswanath De,

Bioorganic & Medicinal Chemistry Letters · 2006 · 37 citations · 4 references

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4

Interferon-induced nuclear signalling by Jak protein tyrosine kinases

Olli Silvennoinen, James N. Ihle, Joseph Schlessinger et al. · Nature · 1993 · 379 citations

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The Novel JAK-3 Inhibitor CP-690550 Is a Potent Immunosuppressive Agent in Various Murine Models

Elizabeth M. Kudlacz, Bret D. Perry, Perry S. Sawyer et al. · American Journal of Transplantation · 2003 · 154 citations

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Selective inhibitor of Janus tyrosine kinase 3, PNU156804, prolongs allograft survival and acts synergistically with cyclosporine but additively with rapamycin

Stanislaw M. Stepkowski, Rebecca Erwin-Cohen, Fariba Behbod et al. · Blood · 2002 · 96 citations · Full text

, , +15

Mapping the kinase domain of janus kinase 3

Christopher Adams, David Aldous, Shelley Amendola et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 50 citations · Full text

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