Bacterial infection and extent of necrosis are determinants of organ failure in patients with acute necrotizing pancreatitis

Abstract

The incidence of organ failure is determined by both bacterial infection and extent of necrosis. The incidence of organ failure is determined by the extent of necrotic parenchyma in patients with sterile necrosis. Infected necrosis is associated with a high incidence of organ failure irrespective of the extent of necrosis.