Biomedicine · 2014 · 14 citations · 0 references
MedicineDermatologyGeneticsDermatopathologyHuman GeneticsPediatric DermatologyCongenital Skin DisordersDysplasiaEctodermal DysplasiasHair DisordersKeratinization DisordersPigmentary DisordersEccrine Gland DisordersEccrine GlandsEccrine Sweat SecretionEctodermal Dysplasia SyndromesEmbryonic Ectoderm PatterningSweat Gland Abnormalities
Ectodermal dysplasia (ED) syndrome comprises a large, heterogeneous group of inherited disorders that are defined by primary defects in the development of 2 or more tissues derived from the embryonic ectoderm. The tissues primarily involved are the skin and its appendages (including hair follicles, eccrine glands, sebaceous glands, nails) and teeth. The clinical features include sparse hair, abnormal or missing teeth, and an inability to sweat due to lack of sweat glands. One such case report of ectodermal dysplasia is presented here.