Significance of Elecsys® S100 immunoassay for real-time assessment of traumatic brain damage in multiple trauma patients

Abstract

Measurements of S100 serum levels using the Elecsys S100 immunoassay are not reliable for the real-time detection of severe TBI in multiple trauma patients. Due to soft tissue trauma or bone fractures, S100 is mainly released from peripheral sources such as adipocytes or skeletal muscle cells.