Isoflurane Attenuates Early Neutrophil-independent Hypoxia-Reoxygenation Injuries in the Reperfused Liver in Fasted Rats

Abstract

The results show that isoflurane protected the liver from an early reoxygenation injury presumably mediated by Kupffer cells. The mechanisms of the inhibitory effects of isoflurane on the injury may involve suppression of extracellular superoxide generation during reoxygenation.